Systemic inflammatory response syndrome, sequential organ failure assessment, and quick sequential organ failure assessment: more pieces needed in the sepsis puzzle

Sepsis remains the most common cause of death in critically ill patients in non-coronary intensive care units (ICUs) (1), while its reported incidence has been steadily increasing during the past three decades (2). Furthermore, many survivors of sepsis would still suffer from long-term physical, psychological, and cognitive disorders (3,4).