Article Abstract

The Sleep Apnea Cardiovascular Endpoints (SAVE) study: implications for health services and sleep research in China and elsewhere

Authors: Zhi-Hui Qiu, Yuan-Ming Luo, R. Doug McEvoy


The results of the Sleep Apnea Cardiovascular Endpoints (SAVE) study were recently published in the New England Journal of Medicine (1). The study recruited 2,717 patients from 89 sites in seven countries. Chinese investigators played a pivotal role in the study with approximately 60% of trial participants recruited from 47 hospital sites. Eight of the top ten recruiting sites were in China including the study’s top recruiting centre.