Article Abstract

Neoadjuvant strategy for stage IIIA-N2 non-small cell lung cancer: chemoradiation or chemotherapy alone?

Authors: Dongrong Situ, Yongbin Lin

Abstract

This pooled study of two phase II trials (RTOG 0229 and 0839) aimed to assess safety and feasibility of anatomic resection following induction therapy with platinum-based chemotherapy and full-dose thoracic radiation for resectable N2 positive stage IIIA non-small cell lung cancer (NSCLC). And it concluded that lobectomy could be performed safely after full-dose concurrent chemoradiation. We would like to discuss this topic further from surgical point of view in the real world.