Outcomes with moderate aortic stenosis and impaired left ventricular function: prelude to a randomized trial?

Alexander Iribarne, Rachel M. Easterwood, Ian C. Bostock, Jock N. McCullough


The natural history of severe, symptomatic aortic stenosis (AS) has been well characterized, with most studies demonstrating a mortality rate of 50% at 2 years once patients develop symptoms of left ventricular (LV) systolic dysfunction (1,2).