Outcomes with moderate aortic stenosis and impaired left ventricular function: prelude to a randomized trial?

Alexander Iribarne, Rachel M. Easterwood, Ian C. Bostock, Jock N. McCullough

Abstract

The natural history of severe, symptomatic aortic stenosis (AS) has been well characterized, with most studies demonstrating a mortality rate of 50% at 2 years once patients develop symptoms of left ventricular (LV) systolic dysfunction (1,2).