Chinese Guideline on allergen immunotherapy for allergic rhinitis

Yixiao Bao, Jianjun Chen, Lei Cheng, Yinshi Guo, Suling Hong, Weijia Kong, He Lai, Houyong Li, Huabin Li, Jing Li, Tianying Li, Xiaoping Lin, Shixi Liu, Zheng Liu, Hongfei Lou, Juan Meng, Qianhui Qiu, Kunling Shen, Wei Tang, Zezhang Tao, Chengshuo Wang, Xiangdong Wang, Qingyu Wei, Li Xiang, Hua Xie, Yu Xu, Gehua Zhang, Yuan Zhang, Yiwu Zheng, Yuxiang Zhi, Dehua Chen, Haiyu Hong, Quansheng Li, Lin Liu, Yifan Meng, Nan Wang, Yihui Wang, Yue Zhou, Luo Zhang, Chinese Society of Allergy (CSA), Chinese Allergic Rhinitis Collaborative Research Group (C2AR2G)

Abstract

The present document is based on a consensus reached by a panel of experts from Chinese Society of Allergy (CSA) and Chinese Allergic Rhinitis Collaborative Research Group (C2AR2G). Allergen immunotherapy (AIT), has increasingly been used as a treatment for allergic rhinitis (AR) globally, as it has been shown to provide a long-term effect in improving nasal and ocular symptoms, reducing medication need, and improving quality of life. AIT is currently the only curative intervention that can potentially modify the immune system in individuals suffering from AR and prevent the development of new sensitization and the progression of disease from AR to asthma. Although the use of AIT is becoming more acceptable in China, to date no AR immunotherapy guideline from China is available for use by the international community. This document has thus been produced and covers the main aspects of AIT undertaken in China; including selection of patients for AIT, the allergen extracts available on the Chinese market, schedules and doses of allergen employed in different routes of AIT, assessment of effect and safety, patients’ administration and follow-up, and management of adverse reactions. The Chinese guideline for AR immunotherapy will thus serve as a reference point by doctors, healthcare professionals and organizations involved in the AIT of AR in China. Moreover, this guideline will serve as a source of information for the international community on AIT treatment strategies employed in China.