Article Abstract

Inequivalence of non-aggressiveness in clinically diagnosed lung cancers and overdiagnosis in lung cancer screening trials

Authors: Jerome M. Reich, Jong S. Kim


Overdiagnosis (OD) designates the screen-identification of cancers which would not have become manifest within the lifetime of an individual due to some combination of indolent growth, immunological editing, limited metastatic potential, loss of vascular supply, and competing lethal morbidities.