Influence of apnoeic oxygenation in respiratory and circulatory system under general anaesthesia

Alexander Kolettas, Vasilis Grosomanidis, Vasilis Kolettas, Paul Zarogoulidis, Kosmas Tsakiridis, Nikolaos Katsikogiannis, Theodora Tsiouda, Ioanna Kiougioumtzi, Nikolaos Machairiotis, Georgios Drylis, Georgios Kesisis, Thomas Beleveslis, Konstantinos Zarogoulidis

Abstract

Apnoeic oxygenation is an alternative technique of oxygenation which is recommended in the consecutive oxygen administration with varying flows (2-10 lt/min) through a catheter which is positioned over the keel of the trachea. Apnoeic oxygenation maintains for a significant period of time the oxygenation of blood in breathless conditions. This technique was first applied in 1947 by Draper, Whitehead, and Spencer and it was studied sporadically by other inventors too. However, the international literature shows few studies that have examined closely apnoeic oxygenation and its effects on Hemodynamic image and the respiratory system of the human body. Recently they have begun to arise some studies which deal with the application of this technique in several conditions such as difficult tracheal intubation, ventilation of guinea pigs in campaign conditions where the oxygen supply is limited and calculable, the application of this technique in combination with the use of extracorporeal removal of carbon dioxide (CO2). All the above indicate, the clinical use of this technique.