Atypical localization of a left atrial myxoma at the free edge of mitral valve

Fabrizio Rosati, Adrian Baranchuk, Kevin Ren, Darrin M. Payne, Andrew Hamilton, Dimitri Petsikas, Gianluigi Bisleri

Abstract

Myxomas represent more than 50% of benign cardiac neoplasm and are the most frequent cardiac tumors (1). Recent studies showed these neoplasms are commonly located in the left atrium (>90%), usually as a pedicled mass arising from the inter-atrial septum at the border of the fossa ovalis (2). Intra-cardiac masses should be differentiated as they could potentially represent a primary or secondary metastatic mass or endocarditis vegetations. We present a case of an exceedingly rare myxoma location, arising from the free-edge of the posterior mitral valve (MV) leaflet, which was incidentally identified in a 20-year-old female investigated for recent onset shortness of breath.