Atypical pulmonary alveolar proteinosis presenting as a mixed nodular ground-glass opacity with focal mucinosis mimicking lung cancer

Tsutomu Shinohara, Hiroyuki Hino, Shino Imanishi, Keishi Naruse, Yuji Ohtsuki, Fumitaka Ogushi


There are various guidelines for the management of a single pulmonary nodule. Although liquid biopsy alone may be able to diagnose lung cancer safely and easily in the future, clinical approaches based on radiological (CT with or without PET) appearance and cancer risk factors are currently common in guidelines.