Sputum purulence-associated microbial community compositions in adults with bronchiectasis

Wei-Jie Guan, Yan Huang, Chun-Lan Chen, Jing-Jing Yuan, Hui-Min Li, Yong-Hua Gao, Rong-Chang Chen, Nan-Shan Zhong


Bronchiectasis is a debilitating chronic inflammatory airway disease which arises from multiple etiologies. The interplay among the etiology, altered microenvironment and defective host-defense may have predisposed to recurrent chest infections of pathogens (1,2) that correlate with bronchiectasis exacerbations and increased mortality.