Article Abstract

Computed tomography characteristics of non-small cell lung cancers with EGFR T790M mutation: role of imaging in the era of precision medicine

Authors: Hyungjin Kim, Hyun-Ju Lee


Early clinical trials investigating the effectiveness of first generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) demonstrated significant prolongation of survival in patients with non-small-cell lung cancers (NSCLCs) harboring sensitizing mutations (1-3), leading to a major shift in the treatment landscape of NSCLCs.