Obstructive sleep apnoea and cardiovascular comorbidity—growing evidence of independent association but recent doubts about benefits from therapy

Obstructive sleep apnoea (OSA) is highly prevalent, affecting up to 50% of the adult male general population (1) and is strongly associated with co-morbidity, especially cardiovascular (2). While the evidence that many co-morbidities such as cardiovascular, metabolic, hepatic, and malignancy are more prevalent in OSA, the evidence of independent association is less clear (3).