Article Abstract

The ABCs of preventing hyperprogressive disease after immunotherapy: awareness, biomarkers, and combination

Authors: Kenichi Suda

Abstract

Hyperprogressive disease is a clinical term that describes the phenomenon of paradoxically accelerated tumor progression after initiation of treatment. Although there is no established definition for hyperprogressive disease, in clinical practice, we do experience patients who show unexpected rapid tumor expansion and poor prognosis even after a pulmonary resection (although it is rare).