Article Abstract

Immunoescape the link between emphysema and lung cancer?

Authors: Jaume Sauleda, Francisco Javier Verdú, Sergio Scrimini, Ernest Sala, Jaume Pons

Abstract

Chronic obstructive pulmonary disease (COPD) has been reported as a risk factor for lung cancer (LC) (1) independently of smoking and mainly related with the presence of emphysema, even in non-smokers (2). The mechanisms of this association are poorly understood. It has been hypothesised that the inflammation and oxidative stress present in COPD could facilitate carcinogenesis (3).