Article Abstract

If you hear hoofbeats, sometimes it is actually a zebra: tumor characteristics and presentation, rather than age, should dictate assessment of esophageal neoplasms

Authors: Tamar Nobel, Daniela Molena


Esophageal sarcomatoid carcinoma (ESC), first described by Virchow in 1864, is a rare neoplasm which contains both a carcinomatous epithelial and sarcomatous stromal component. Comprising 0.3–2.8% of esophageal malignancies, its description in the literature is predominantly composed of individual patient reports and small case series spanning large time intervals (1-6).