Extensive abdominal and chest wall resection and reconstruction for invasive squamous cell carcinoma of the skin

Pia Ferrigno, Nicola Monaci, Alessandro Pangoni, Giovanni Comacchio, Giuseppe Natale, Eleonora Faccioli, Andrea Zuin, Andrea Dell’Amore, Federico Rea


The effective incidence of cutaneous squamous cell carcinoma of the skin (cSCC) is unknown, in general cSCC is the second most common skin cancer, accounting for 20% of all cutaneous malignancies, with a continuous increase in its frequency (1). The skin of the thorax is a very rare localization for this kind of tumor (1-4). Despite cSCC is a malignant proliferation of keratinizing cells of the epidermis, generally, when the diagnosis is made, early surgical resection with adequate surgical margins is curative in more than 95% of the cases (5). Here we present a very rare case of local recurrence of a huge cSCC involving the anterior chest wall that underwent extensive chest wall resection associated to complex reconstruction by using a combination of synthetic materials and autologous flaps.