Is the length of esophageal invasion only associated with mediastinal nodal metastasis from adenocarcinoma of the esophagogastric junction (Siewert type II and III) after neo-adjuvant chemoradiotherapy?

Shinji Mine


I recently read Dr. Mitchell and his/her colleagues’ article with great interest (1). They investigated the association between thoracic nodal involvement and clinical factors in patients who underwent surgical resection for Siewert type II or III adenocarcinoma after neoadjuvant chemoradiotherapy. They concluded that thoracic nodal involvement was more strongly associated with the length of esophageal invasion than with the location of the tumor’s epicenter (Siewert type classification).