Role of imaging in predicting tumor spread through airspaces (STAS): what are the next steps

Constance de Margerie-Mellon, Paul A. VanderLaan, Benedikt H. Heidinger, Alexander A. Bankier


Tumor spread through airspaces (STAS) has been identified as a new pattern of invasion in the 2015 WHO classification of lung tumors (1) and is associated with a lower overall survival in resected non-small cell lung cancers (2). As a consequence, sublobar resection may not be the best surgical option for cancers with STAS.