010. Coronary artery bypass in prior left pneumonectomy postoperative use of iloprost
The Pan Hellenic Congress Abstracts

010. Coronary artery bypass in prior left pneumonectomy postoperative use of iloprost

Agisilaos Ignatiadis, Fotini Ampatzidou, George Kechagioglou, Konstantinos Antoniou, Nikolaos Michail, Theodoros Karaiskos, Maria Sileli, George Drossos

Department of Cardiothoracic Surgery, General Hospital ‘G. Papanikolaou’, Thessaloniki, Greece


Background: The rare procedure of coronary artery bypass in a prior left pneumonectomy patient characterized by postoperative cardiopulmonary complications. Acute right heart failure due to anatomic and physiologic changes because of pneumonectomy is the most serious complication. It is very helpful to prevent this condition by reducing pulmonary vascular resistance index which represents the right heart afterload. In our case we have recorded the favorable hemodynamic effects of inhaled Iloprost.

Methods: A 60-year-old man presented to our department with acute coronary syndrome. He had undergone a left pneumonectomy nine years ago because of bronchial carcinoma. Coronary angiography, which was performed during acute coronary syndrome, revealed left main disease (70% stenosis) and 50% stenosis in right coronary artery. Pulmonary function tests revealed severe restrictive disease: forced vital capacity (FVC): 1.47 L (30% of predicted) and forced expiratory volume (FEV) 1: 1.41 L (25% of predicted). Coronary artery bypass surgery (CABG) procedure was successfully completed with cardiopulmonary bypass (CPB) and patient was transferred in ICU. Patient’s inotropic support was 0.1 μg/kg/min Epinephrine and 0.06 μg/kg/min Noradrenaline. In the ICU, in order to avoid RV dysfunction the patient was ventilated with low tidal volume, Vt 6 mL/kg and with low positive end-expiratory pressure (PEEP). He was under careful fluid balance. Hemodynamic profile revealed high values of PVRI. This undesirable high RV afterload was managed with inhaled Iloprost (prostacyclin analogue) because of its elective pulmonary vessels dilator properties.

Results: The patient was extubated 5 hours postoperatively. Postoperative vigorous chest physiotherapy and bronchodilation due to transient brochospasm contributed to the uncomplicated respiratory function. The patient discharged on 7th postop day.

Conclusions: CABG in postpneumonectomy patients is a challenging procedure. The use of selective pulmonary vasodilators could offer better postoperative conditions in order to overcome the possible cardiorespiratory complications in this group of patients.

Keywords: Iloprost; pulmonary hypertension; transplantation


doi: 10.3978/j.issn.2072-1439.2015.AB010


Cite this abstract as: Ignatiadis A, Ampatzidou F, Kechagioglou G, Antoniou K, Michail N, Karaiskos T, Sileli M, Drossos G. Coronary artery bypass in prior left pneumonectomy postoperative use of iloprost. J Thorac Dis 2015;7(S1):AB010. doi: 10.3978/j.issn.2072-1439.2015.AB010

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