Guillain-Barré syndrome in two patients with respiratory failure and a review of the Japanese literature

Erei Sohara, Takeshi Saraya, Kojiro Honda, Atsuko Yamada, Toshiya Inui, Yukari Ogawa, Mitsuru Sada, Naoki Tsujimoto, Masuo Nakamura, Akiko Tsuchiya, Masaki Saito, Chizuko Oishi, Atsuro Chiba, Hajime Takizawa, Hajime Goto


We described two patients with Guillain-Barré syndrome and respiratory failure with or without mechanical ventilation. Case 1 was a 44-year-old man who treated as pneumonia under mechanical ventilation for a month and transferred to our hospital with unsuccessful weaning trials because of phrenic nerve palsy. Case 2 was a 74-year-old man who presented with aspiration pneumonia because of bulbar palsy. The present two cases with review of the Japanese literature showed that antecedent infection with initial symptoms within the most recent 5 to 46 days is a clinical clue to the diagnosis even in patients with Guillain-Barré syndrome accompanied by respiratory failure.