AB 31. Solitary fibrous tumor (SFT) of the lung:
review of five cases
Background: Solitary fibrous tumor (SFT) of the pleura and the lung is
an uncommon spindle cell neoplasm, usually presented as a peripheral
mass, arising from the visceral pleura in the majority of the cases. Inward
growth into the lung’s parenchyma is rare. The tumor is common during
the fifth and sixth decades with no sex predominance. We describe five
cases diagnosed to our department as solitary fibrous tumor (SFT) of
Patients and methods: For the past ten years, five patients, from 46 to
67 years old, were presented to our hospital with intrapulmonary, wellcircumscribed
nodule. Thus, due to a diagnostic confirmation of the
pulmonary nodule, surgery was performed and the lesion was removed
in all five cases.
Results: Histologically, the tumors were characterized by the
coexistence of hypo- and hypercellular areas, separated by fibrous
stroma which had haemangiopericytoma-like branching blood vessels.
The hypercellular areas were composed of bland spindle cells arranged
in short intersecting fascicles, creating storiform arrays. The hypocellular
areas presented myxoid changes in some cases. Immunohistochemical
stains for CD34 and bcl-2 were positive in all cases. Morphological and
immunohistochemical findings consistent with solitary fibrous tumor
(SFT) of the lung.
Conclusions: Solitary fibrous tumor (SFT) of the lung is an
uncommon mesenchymal tumor entity. Although rare, the diagnosis
should be considered in asymptomatic slow growing pulmonary
nodules. Resection with clear margins is the main important prognostic factor.
Cite this abstract as: Baliaka A, Iordanidis F, Tryfon S, Pastelli N, Sakkas L.
Solitary fibrous tumor (SFT) of the lung: review of five cases. J Thorac Dis
2012;4(S1):AB31. DOI: 10.3978/j.issn.2072-1439.2012.s031