Background: Diffuse pulmonary ossification is a rare abnormal finding
characterized by the formation of mature bone tissue both in the
interstitium and in the cells, with or without evidence of bone marrow.
May be idiopathic or associated with chronic pulmonary, cardiac
or systemic diseases. Men are affected more often than the women,
usually between the sixth and eighth decade of life. They described two
histologic types of pulmonary ossification: the perigraptos nodular
(nodular) type and 2) dendritic (dendriform) guy. The purpose of this
paper is to present an event with diffuse pulmonary ossification in a
better understanding of the entity and membership in the differential
diagnosis of interstitial lung disease.
Patients and methods: This man, 68 year old former smoker with a
history of coronary heart disease, hypertension, chronic bronchitis,
which was referred to the Cardiac Clinic G.N.TH. “C. Smear “because
persistent pneumothorax. Under investigation, computed tomography
(CT) chest revealed multiple bilateral cysts sizeable gaseous, multiple nodules in the lower lobes ypoupezokotika lung and presence of
pneumothorax in the left hemithorax. Mini left thoracotomy was
performed and received bioptic material.
Results: Histological examination showed lung parenchyma with
the presence of multiple cystic formations with fibrin in the wall and
a reduction of the pulmonary parenchyma. In several places there
ossified tissue with presence myelochoron and bone marrow cells in
afton. I diagnosis was entered: lung parenchyma with the presence
emfysimatikon cysts and foci of ossification.
Conclusions: Diffuse pulmonary ossification remains underdiagnosed
during life. Most cases are an incidental finding at autopsy, and that the
absence of symptoms. An early diagnosis will allow for better treatment
of the natural course of the disease, while paving the way for new