Bronchial thermoplasty (BT) is a non-pharmacologic therapy for severe asthma. The proper procedure and perioperative management are very important for the effectiveness and safety of BT. China Asthma Alliance assembled a group of experts in asthma and BT to review the literature, drew on their own experiences, discussed, and then nalized by consensus to establish this standard practice guideline. This practice guideline is designed to guide clinicians as to proper patients’ selection, preoperative assessment, postoperative management and follow-up. This practice guideline also proposed “China Alair System Registry Study (NCT02206269)” as the real-world study to enhance clinical utility of BT.