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Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition

	author = {Paul Zarogoulidis and Aggeliki Cheva and Katerina Zarampouka and Haidong Huang and Chen Li and Yong Huang and Nikolaos Katsikogiannis and Konstantinos Zarogoulidis},
	title = {Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition},
	journal = {Journal of Thoracic Disease},
	volume = {5},
	number = {3},
	year = {2013},
	keywords = {},
	abstract = {Nutrition has been known for ages to shield the immune system against several formulations that deregulate normal DNA repair mechanisms, and induce tumorigenesis. Vitamins and in specific Vit E and its members tocopherols (α-, β-, γ-, δ-) and tocotrienols (α-, β-, γ-, δ-) have demonstrated strong association with the prevention of cancer and inhibition of tumor, both in vitro and in vivo. Vitamin E has also demonstrated effective role against chemotherapy resistant cancer cell evolution and a protective role in acute interstitial disease. Several formulations of Vitamin E have been investigated conjugated with different carriers as nano-formulations and administered in different forms. Additionally, several tumorigenic pathways have been investigated separately in an effort to identify which member of Vitamin E inhibits efficiently every pathway. Vitamin E presented efficiency against specific subhistology types of lung cancer. Finally, in the current work up to date information regarding novel formulations with Vitamin E and inhibition pathways are going to be presented and commented.},
	issn = {2077-6624},	url = {}