TY - JOUR AU - Zarogoulidis, Paul AU - Cheva, Aggeliki AU - Zarampouka, Katerina AU - Huang, Haidong AU - Li, Chen AU - Huang, Yong AU - Katsikogiannis, Nikolaos AU - Zarogoulidis, Konstantinos PY - 2013 TI - Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition JF - Journal of Thoracic Disease; Vol 5, No 3 (June 26, 2013): Journal of Thoracic Disease Y2 - 2013 KW - N2 - Nutrition has been known for ages to shield the immune system against several formulations that deregulate normal DNA repair mechanisms, and induce tumorigenesis. Vitamins and in specific Vit E and its members tocopherols (α-, β-, γ-, δ-) and tocotrienols (α-, β-, γ-, δ-) have demonstrated strong association with the prevention of cancer and inhibition of tumor, both in vitro and in vivo. Vitamin E has also demonstrated effective role against chemotherapy resistant cancer cell evolution and a protective role in acute interstitial disease. Several formulations of Vitamin E have been investigated conjugated with different carriers as nano-formulations and administered in different forms. Additionally, several tumorigenic pathways have been investigated separately in an effort to identify which member of Vitamin E inhibits efficiently every pathway. Vitamin E presented efficiency against specific subhistology types of lung cancer. Finally, in the current work up to date information regarding novel formulations with Vitamin E and inhibition pathways are going to be presented and commented. UR - https://jtd.amegroups.org/article/view/1045