TY - JOUR AU - Ge, Jin AU - Verma, Vivek AU - Hollander, Andrew AU - Langer, Corey AU - Simone II, Charles B. PY - 2016 TI - Pemetrexed-induced radiation recall dermatitis in a patient with lung adenocarcinoma: case report and literature review JF - Journal of Thoracic Disease; Vol 8, No 12 (December 31, 2016): Journal of Thoracic Disease Y2 - 2016 KW - N2 - Radiation recall dermatitis (RRD) is an inflammatory reaction in a previously irradiated field subsequent to the administration of pharmacologic or promoting agents. Herein, we describe a 47-year-old man with NSCLC who was treated with radiotherapy and pemetrexed-based chemotherapy three years prior to developing RRD upon resumption of pemetrexed-based chemotherapy. RRD with pemetrexed is rare and consists of five cases reported thus far. Although RRD is a rare phenomenon, it should be considered in any patient with dermatologic reactions that occur at the site of previous exposure to radiation therapy. When severe, RRD can pose a significant, and possibly life-threatening, impediment to the treatment and care of oncology patients. We discuss the time course, natural history, and management of this condition, as well as a connection to internal organ involvement, such as pneumonitis in thoracic oncology patients. UR - https://jtd.amegroups.org/article/view/11231