TY - JOUR AU - Lockney, Natalie A. AU - Wu, Abraham J. PY - 2017 TI - Alectinib for the management of ALK-positive non-small cell lung cancer brain metastases JF - Journal of Thoracic Disease; Vol 9, No 2 (February 28, 2017): Journal of Thoracic Disease Y2 - 2017 KW - N2 - Anaplastic lymphoma kinase ( ALK ) rearrangements were first identified as an oncogenic driver in non-small cell lung cancers (NSCLC) in 2007, specifically the gene re-arrangement between ALK and echinoderm microtubule-associated protein like 4 ( EML4 ) (1). UR - https://jtd.amegroups.org/article/view/12088