TY - JOUR AU - Wu, Hai-Bo AU - Ma, Wei-Guo AU - Zhao, Hong-Lei AU - Zheng, Jun AU - Li, Jian-Rong AU - Liu, Ou AU - Sun, Li-Zhong PY - 2017 TI - Risk factors for continuous renal replacement therapy after surgical repair of type A aortic dissection JF - Journal of Thoracic Disease; Vol 9, No 4 (April 25, 2017): Journal of Thoracic Disease Y2 - 2017 KW - N2 - Background: To identify the risk factors for continuous renal replacement therapy (CRRT) following surgical repair of type A aortic dissection (TAAD) using the total arch replacement and frozen elephant trunk (TAR + FET) technique. Methods: The study included 330 patients with TAAD repaired using TAR + FET between January 2014 and April 2015. Mean age was 47.1±10.2 years (range, 18–73 years) and 242 were male (73.3%). Univariate and multivariate analyses were used to identify the risk factors for CRRT. Results: Postoperative CRRT was required in 38 patients (mean age 50.7±10.0 years; 27 males). Operative death occurred in 12 patients (3.6%, 12/330). The mortality rate was 23.7% (9/38) in patients with CRRT and 1.0% (3/292) in those without CRRT (P vs . 46.7±10.2 years, P=0.023), preoperative serum creatinine (sCr) (135.0±154.2 vs . 85.7±37.0 μmol/L, P vs . 73.3%, P=0.030), cardiopulmonary bypass (CPB) time (265.2±98.8 vs . 199.7±44.2 minutes, P vs . 116.3±33.2 minutes, P vs . 3.7±3.3 unit, P vs . 784.2±488.5 mL, P vs . 2,856.7 mg/L, P vs . 2.4%, P Conclusions: In this series of patients with TAAD, the time of CPB (minute), sCr level (μmol/L) and the amount of red blood cell transfused intraoperatively (unit) were risk factors for CRRT after TAR + FET. UR - https://jtd.amegroups.org/article/view/13118