TY - JOUR AU - McCullar, Brennan AU - Alloway, Taylor AU - Martin, Michael PY - 2017 TI - Durable complete response to nivolumab in a patient with HIV and metastatic non-small cell lung cancer JF - Journal of Thoracic Disease; Vol 9, No 6 (June 29, 2017): Journal of Thoracic Disease Y2 - 2017 KW - N2 - Programmed death 1 (PD-1) inhibitors have been shown to increase overall survival in non-small cell lung cancer (NSCLC) patients. HIV patients have increased expression of PD-1 on their T-cell surfaces. We describe a patient with well-controlled HIV and NSCLC who underwent treatment with nivolumab and had a durable complete response (CR) with his viral load remaining undetectable. To date there is only one case report of a cancer patient with melanoma and with HIV treated with a programmed death ligand 1 (PD-L1) inhibitor. The majority of clinical trials involving PD-1 and PD-L1 inhibitors exclude HIV patients. UR - https://jtd.amegroups.org/article/view/13605