%0 Journal Article %T The value of positive lymph nodes ratio combined with negative lymph node count in prediction of breast cancer survival %A Yang, Jing %A Long, Quanyi %A Li, Hongjiang %A Lv, Qing %A Tan, Qiuwen %A Yang, Xiaoqin %J Journal of Thoracic Disease %D 2017 %B 2017 %9 %! The value of positive lymph nodes ratio combined with negative lymph node count in prediction of breast cancer survival %K %X Background: Positive lymph node ratio (LNR), defined as ratio of positive lymph nodes to all lymph nodes removed, is a powerful prognostic factor in invasive breast cancer. Here we focused on the impact of negative lymph node (NLN) count on the prediction of value of LNR in breast cancer survival. Methods: Of 929 invasive breast cancer patients were enrolled in our retrospective study. We use Kaplan-Meier to calculate the 5-year overall survival (OS) according to different clinicopathologic parameters. The prediction value of NLN count and LNR in OS was examined. Results: The optimal cutoff of NLN count was designated as 9. Five-year OS was 77.0% and 95.0% in patients with NLN of 0–9 and ≥10, respectively (P Conclusions: High NLN count is associated with improved survival in invasive breast cancer patients. Combining NLN count with LNR could be considered as an alternative to LNR alone in prediction of postoperative breast cancer survival. %U https://jtd.amegroups.org/article/view/13610 %V 9 %N 6 %P 1531-1537 %@ 2077-6624