@article{JTD14108,
author = {Song Liu and Huanhuan Zheng and Xia Pan and Ling Chen and Minke Shi and Yue Guan and Yun Ge and Jian He and Zhengyang Zhou},
title = {Texture analysis of CT imaging for assessment of esophageal squamous cancer aggressiveness},
journal = {Journal of Thoracic Disease},
volume = {9},
number = {11},
year = {2017},
keywords = {},
abstract = {Background: To explore the role of texture analysis of computed tomography (CT) images in preoperative assessment of esophageal squamous cell carcinoma (ESCC) aggressiveness.
Methods: Seventy-three patients with pathologically confirmed ESCC underwent unenhanced and contrast enhanced CT imaging preoperatively. Texture analysis was performed on unenhanced and contrast enhanced CT images, respectively. Six CT texture parameters were obtained. One-way analysis of variance or independent-samples t-test (normality), independent-samples Kruskal-Wallis test or Mann-Whitney U test (non-normality), binary Logistic regression analysis (multivariable), Spearman correlation test, receiver operating characteristic (ROC) curve analysis and intraclass correlation coefficient (ICC) were used for statistical analyses.
Results: Kurtosis was an independent predictor for T stages (T1–2 vs. T3–4) as well as overall stages (I–II vs. III–IV) based on unenhanced CT images, while entropy was an independent predictor for T stages (T1–2 vs. T3–4), lymph node metastasis (N− vs. N+) and overall stages (I/II vs. III/IV). Skew and kurtosis based on unenhanced CT images showed significant differences among N stages (N0, N1, N2 and N3) as well as 90th percentile based on contrast enhanced CT images. In correlation with T stage of ESCC, kurtosis and entropy significantly correlated with T stage both on unenhanced and contrast enhanced CT images. Reversely, entropy and 90th percentile based on contrast enhanced CT images showed significant correlations with N stage (r: 0.526, 0.265; both P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/14108}
}