%0 Journal Article %T Cigarette smoke-induced autophagy: a deadly association? %A Pallet, Nicolas %J Journal of Thoracic Disease %D 2017 %B 2017 %9 %! Cigarette smoke-induced autophagy: a deadly association? %K %X Cigarette smoke, and the mutagen agents it contains, is a universal conveyor of DNA alterations in the pulmonary airway cells, ultimately leading to cancer. In addition, the thousands xenobiotics and pro-oxidant agents contained in smoke participate in the pathophysiology of chronic obstructive pulmonary diseases (COPD) and emphysema by inducing cell death, chronic inflammation, and deregulated extracellular matrix degradation and remodeling. %U https://jtd.amegroups.org/article/view/14898 %V 9 %N 8 %P 2228-2230 %@ 2077-6624