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Pulmonary metastasectomy in uterine malignancies: outcome and prognostic factors

	author = {Marco Anile and Sara Mantovani and Ylenia Pecoraro and Carolina Carillo and Lorenzo Gherzi and Andreina Pagini and Erino Angelo Rendina and Federico Venuta and Daniele Diso},
	title = {Pulmonary metastasectomy in uterine malignancies: outcome and prognostic factors},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {12},
	year = {2017},
	keywords = {},
	abstract = {Background: This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers. 
Methods: Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies. 
Results: Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40.9% and 31.4%, respectively. Five-year survival in patients receiving adjuvant therapy was 52.4%. At multivariate analysis factors negatively influencing survival were a disease-free interval (DFI) of less than 24 months and recurrence after pulmonary metastasectomy. 
Conclusions: Pulmonary resection for metastatic gynecologic cancer is feasible and effective; adequate selection of patients is mandatory to achieve satisfactory results and long-term survival.},
	issn = {2077-6624},	url = {}