TY - JOUR AU - Hu, Zhiwei PY - 2017 TI - The future of immune checkpoint blockade immunotherapy: towards personalized therapy or towards combination therapy JF - Journal of Thoracic Disease; Vol 9, No 11 (November 29, 2017): Journal of Thoracic Disease (Quantitative Imaging of Thoracic Diseases) Y2 - 2017 KW - N2 - One of the major breakthroughs in cancer immunotherapy in the past decades was the discovery of immune checkpoint molecules, notably cytotoxic T-lymphocyte associated protein 4 (CTLA-4) (1) and the programmed cell death-1 (PD-1, also known as CD279) T-cell receptor (2) and its ligands (programmed death-ligand 1 (PD-L1, also known as B7-H1 or CD274) (3) and PD-L2 (also known as B7-DC or CD273) (4). UR - https://jtd.amegroups.org/article/view/16516