TY - JOUR AU - Lee, Hyun AU - Um, Sang-Won PY - 2017 TI - Intratumoral heterogeneity and biomarkers for transformation into small cell lung carcinomas from lung adenocarcinomas JF - Journal of Thoracic Disease; Vol 9, No 11 (November 29, 2017): Journal of Thoracic Disease (Quantitative Imaging of Thoracic Diseases) Y2 - 2017 KW - N2 - Recent advances in next-generation sequencing have opened a new prospect in the field of cancer genomics and cancer evolution. Using next-generation sequencing, researchers have revealed that the occurrence of somatic events such as mutations and copy number alterations is associated with tumor evolution and genomic diversity in tumors, which is known as tumor heterogeneity (1). UR - https://jtd.amegroups.org/article/view/16983