TY - JOUR AU - Yang, Yikun AU - Mao, Yousheng AU - Yang, Lin AU - He, Jie AU - Gao, Shugeng AU - Mu, Juwei AU - Xue, Qi AU - Wang, Dali AU - Zhao, Jun AU - Gao, Yushun AU - Zhang, Zhirong AU - Ding, Ningning AU - Yang, Ding PY - 2017 TI - Prognostic factors in curatively resected pathological stage I lung adenocarcinoma JF - Journal of Thoracic Disease; Vol 9, No 12 (December 29, 2017): Journal of Thoracic Disease Y2 - 2017 KW - N2 - Background: Patients with pathological stage I (p I) lung adenocarcinoma show variabilities in prognosis even after complete resection. The factors resulting in heterogeneities of prognosis remain controversy. The aim of this study was to identify the risk factors affecting recurrence/metastasis and survival in patients with curatively resected p I lung adenocarcinoma. Methods: A total of 252 patients with p I lung adenocarcinoma underwent curative resection between January 1th, 2009 to September 30th, 2011 were retrospectively reviewed to analyze the associations of recurrence and survival with the following clinicopathological variables: gender, age, cigarette smoking, family cancer history, tumor size, TNM stage, tumor differentiation, visceral pleural invasion, bronchial involvement, lymphovascular invasion, postoperative adjuvant treatment, pathological subtypes and micropapillary pattern. Results: Among those 252 patients, 48 had local recurrence or distant metastasis, the rest 204 patients had no relapse until the last follow-up. Cox univariate survival analysis revealed that tumor size (P Conclusions: Tumor size, TNM stage, tumor differentiation, bronchial involvement, lymphovascular invasion and micropapillary pattern could be considered as risk factors for predicting local recurrence or distant metastasis and survival in curatively resected p I lung adenocarcinoma patients. UR - https://jtd.amegroups.org/article/view/17432