TY - JOUR AU - Florés, Marina AU - Martinez-Alonso, Montserrat AU - Sánchez-de-la-Torre, Alicia AU - Aldomà, Albina AU - Galera, Estefania AU - Barbé, Ferran AU - Sánchez-de-la-Torre, Manuel AU - Dalmases, Mireia PY - 2018 TI - Predictors of long-term adherence to continuous positive airway pressure in patients with obstructive sleep apnoea and acute coronary syndrome JF - Journal of Thoracic Disease; Vol 10, Supplement 1 (January 24, 2018): Journal of Thoracic Disease (Dedicated to the 3rd Clinical Update Sleep: International Conference 2018, Endorsed by ERS) Y2 - 2018 KW - N2 - Background: Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea (OSA), but an evaluation of CPAP adherence is rarely carried out among patients with acute coronary syndrome (ACS). The goals of the study are to analyse long-term adherence and identify the predictors of non-compliance with CPAP treatment for patients with non-sleepy OSA and ACS. Methods: This is an ancillary study of the ISAACC study, which is a multicentre, prospective, open-label, parallel, randomized, and controlled trial (NCT01335087) in patients with hospital admission for ACS. For the purpose of this study, only non-sleepy patients with moderate or severe OSA and randomized to receive CPAP treatment were analysed (n=357). Non-compliance was defined as CPAP dropout or average cumulative CPAP use of Results: Adherence to treatment was 35.3% at 12 months. According to the unadjusted analysis, higher apnoea-hypopnea index (AHI) (P Conclusions: Protective factors against non-compliance with CPAP treatment in non-sleepy patients with ACS were illness severity (high values of AHI or ICU stay length) or smoking amount. Patients with no previous history of ACS showed lower odds of CPAP non-compliance than patients with a recurrent ACS with younger age. UR - https://jtd.amegroups.org/article/view/18279