TY - JOUR AU - Liang, Wenhua AU - Zhao, Yi AU - Huang, Weizhe AU - Liang, Hengrui AU - Zeng, Haikang AU - He, Jianxing PY - 2018 TI - Liquid biopsy for early stage lung cancer JF - Journal of Thoracic Disease; Vol 10, Supplement 7 (April 18, 2018): Journal of Thoracic Disease (Early Detection and Diagnosis of Lung Cancer) Y2 - 2018 KW - N2 - Liquid biopsy, which analyzes biological fluids especially blood specimen to detect and quantify circulating cancer biomarkers, have been rapidly introduced and represents a promising potency in clinical practice of lung cancer diagnosis and prognosis. Unlike conventional tissue biopsy, liquid biopsy is non-invasive, safe, simple in procedure, and is not influenced by manipulators’ skills. Notably, some circulating cancer biomarkers are already detectable in disease with low-burden, making liquid biopsy feasible in detecting early stage lung cancer. In this review, we described a landscape of different liquid biopsy methods by highlighting the rationale and advantages, accessing the value of various circulating biomarkers and discussing their possible future development in the detection of early lung cancer. UR - https://jtd.amegroups.org/article/view/20441