%0 Journal Article %T Limited prognostic value of myocardial viability assessment in patients with coronary artery diseases and severe left ventricular dysfunction %A Liu, Yihua %A Jiang, Yefan %A Yang, Xiaoxi %A Geng, Bingchuan %A Liu, Yi %A Shang, Xiaoke %A Liu, Jinping %A Lan, Xiaoli %A Dong, Nianguo %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Limited prognostic value of myocardial viability assessment in patients with coronary artery diseases and severe left ventricular dysfunction %K %X Background: Myocardial viability assessment is typically performed in patients with coronary artery disease (CAD) and severe left ventricular (LV) dysfunction to identify those who might benefit from revascularization and assist in decision making process. However, the prognostic value of myocardial viability testing remains a debating issue. Methods: Positron Emission Tomography using 18 F-fluorodeoxyglucose ( 18 FDG-PET) was performed in 81 patients with ischemic LV dysfunction [ejection fraction (EF) ≤35%] for myocardial viability assessment prior to coronary artery bypass surgery. Fifty-three of them received finally coronary artery bypass grafting and were divided into two groups according to the extent of myocardial scar: one group with scar burden ≥10% (n=30) and the other with scar burden Results: 18 FDG-PET revealed a different profile of myocardial viability among three groups with respect to the extent of myocardial scar, the hibernating myocardium (both P Conclusions: Myocardial viability assessment using 18 FDG-PET is of limited prognostic value in patients with CAD and severe LV dysfunction. In patients with substantial myocardial scar burden despite the existence of considerable hibernating myocardium, functional recovery following surgical revascularization is not necessarily translated to survival benefits. %U https://jtd.amegroups.org/article/view/20550 %V 10 %N 4 %P 2249-2255 %@ 2077-6624