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Impact of the favorable prognosis of patients with lung cancer adjoining bullae

	author = {Shuichi Shinohara and Masakazu Sugaya and Takamitsu Onitsuka and Kazuhiko Machida and Masaki Matsuo and Kazuo Kato and Fumihiro Tanaka},
	title = {Impact of the favorable prognosis of patients with lung cancer adjoining bullae},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {6},
	year = {2018},
	keywords = {},
	abstract = {Background: Lung cancer adjoining bullae (LC-AB) is an uncommon manifestation. The clinical characteristics and prognosis of LC-AB remain unclear. The aim of this study is to investigate the clinical features and overall survival (OS) of patients with LC-AB following lung resection compared to non-LC-AB group.
Methods: We retrospectively investigated 291 consecutive patients with lung cancer who underwent curative resection in a single institution between April 2007 and March 2015. A total of LC-AB was 52 patients. LC-AB was determined using thin slice computed tomography (CT) imaging and pathological findings. Survival analysis was calculated using the Kaplan-Meier method. We used a Cox proportional hazards model for the univariate and multivariate analysis to identify prognostic factors.
Results: The LC-AB group showed a higher frequency of younger patients (P=0.017), former or current smokers (P=0.011), men (P=0.021), tumor location in the upper lobe (P=0.031), moderately or poorly differentiated tumor histology (P},
	issn = {2077-6624},	url = {}