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Surgery for pulmonary metastases from colorectal cancer: survival and prognostic factors

  
@article{JTD21747,
	author = {Mamdoh Al-Ameri and Michael Persson and Per Bergman and Anders Franco-Cereceda and Ulrik Sartipy},
	title = {Surgery for pulmonary metastases from colorectal cancer: survival and prognostic factors},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {6},
	year = {2018},
	keywords = {},
	abstract = {Background: This study aimed to describe overall survival following pulmonary metastasectomy for colorectal cancer (CRC) in Sweden, and to assess the discrimination of a recently proposed risk prediction model.
Methods: Individual-level data of 756 patients who underwent resection of pulmonary metastases from CRC between 2009 and 2015 were obtained from ThoR, a Swedish national quality register for thoracic surgery. We classified patients into three risk categories according to the number of preoperative risk factors [age, disease-free interval (DFI), presence of extrathoracic lesions, number of pulmonary metastases] established in a prior study. We estimated the hazard ratios (HRs) and 95% confidence interval (CI) by Cox regression and the restricted mean survival time difference as group contrast measures.
Results: During a median follow-up time of 2.9 years, 35% (268/756) patients died. At 5 years, overall survival was 56% (95% CI: 51–60%). In a Cox regression model with risk category as the only independent variable, the HR for all-cause mortality was 1.94 (95% CI: 1.38–2.72, P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/21747}
}