%0 Journal Article %T Health-related quality of life evaluation in patients with nonsurgical benign tracheal stenosis %A Bibas, Benoit Jacques %A Guerreiro Cardoso, Paulo Francisco %A Salati, Michele %A Minamoto, Helio %A Luiz Tamagno, Mauro Federico %A Terra, Ricardo Mingarini %A Pêgo-Fernandes, Paulo Manuel %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Health-related quality of life evaluation in patients with nonsurgical benign tracheal stenosis %K %X Background: The primary objective of the study was to evaluate the health-related quality of life (HRQL) of patients with benign post-intubation tracheal stenosis considered as unfit for surgical treatment. Secondary objectives were: (I) to determine if clinical variables (gender, age, total treatment time, and type of tracheal device) could influence HRQL and (II) to compare the results with a normal standardized population. Methods: Prospective study between August-2014 and December-2016 including patients with tracheal stenosis treated with silicone stents, T-Tubes or tracheostomy. Candidates to airway resection and reconstruction were excluded from the analysis. HRQL was assessed with the SF-36 Health Questionnaire. Backward stepwise regression model analyzed the influence of clinical variables on the SF-36 domains and component summaries. Norm-based results were compared with normative data. Alpha error was 5%. Results: Ninety-three patients (62M/31F; mean age 38±14 years) were included. Mean overall HRQL in all 8 SF-36 domains was poor. Lowest scores were in the role physical (mean 31.7±38), bodily pain (mean 39.2±35), and role emotional domain (mean 48.7±40). The physical component summary (PCS) was more affected than the mental (P Conclusions: Quality of life of patients with benign tracheal stenosis is severely impaired, and norm-based results indicate that the HRQL is below normative data. Physical and mental discomfort seems to be attenuated by total treatment time. %U https://jtd.amegroups.org/article/view/22935 %V 10 %N 8 %P 4782-4788 %@ 2077-6624