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Application of albumin/globulin ratio in elderly patients with acute exacerbation of chronic obstructive pulmonary disease

  
@article{JTD23095,
	author = {Jinqiu Qin and Yuanyuan Qin and Yangyang Wu and Aiqiu Wei and Meiling Luo and Lin Liao and Faquan Lin},
	title = {Application of albumin/globulin ratio in elderly patients with acute exacerbation of chronic obstructive pulmonary disease},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {8},
	year = {2018},
	keywords = {},
	abstract = {Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has become an important disease of hospitalized elderly patients, which lack simple and inexpensive indicators for evaluating the condition and prognosis. This study was performed to investigate the clinical significance of the serum albumin/globulin ratio (AGR) in elderly patients with AECOPD. 
Methods: The data of 252 hospitalized elderly patients with AECOPD, 89 stable COPD patients and 115 elderly healthy individuals were analyzed and compared. The differences in the AGR, logarithm of the serum C-reactive protein (LogCRP) level, prealbumin (PA) level, and immunoglobulin G (IgG) level were compared. AECOPD patients were grouped using the optimal cutoff values of each index to compare the difference in the combined infection rate. The correlation between hospital stays and AGR was analyzed. 
Results: The AGR, LogCRP, PA level, and IgG level were different among the AECOPD group, stable COPD group and healthy control groups (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/23095}
}