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Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients

  
@article{JTD23135,
	author = {Samaresh Sau and Arun K. Iyer},
	title = {Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {8},
	year = {2018},
	keywords = {},
	abstract = {In the tumor microenvironment, overexpression of check point molecules, such as program death ligand-1 (PDL1) functions as a protector against the immune surveillance by T-cell through the interaction with program death-1 (PD1) receptor (1). It has been found that PD1 overexpressed on a variety of tumor-killing immune cells, such as monocytes, macrophages, cytotoxic CD8+ T cells, and dendritic cells has an active role in hijacking the antitumor immune response (2).},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/23135}
}