@article{JTD23357,
author = {Makoto Odaka and Yuki Noda and Yo Tsukamoto and Daiki Kato and Takamasa Shibasaki and Shohei Mori and Hisatoshi Asano and Hideki Matsudaira and Makoto Yamashita and Toshiaki Morikawa},
title = {Impact of the introduction of thoracoscopic lobectomy for non-small cell lung cancer: a propensity score-matched analysis},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {8},
year = {2018},
keywords = {},
abstract = {Background: The present study evaluated the impact of the introduction of thoracoscopic lung lobectomy (TL) for non-small cell lung cancer at our institution.
Methods: This study retrospectively compared surgical and oncological outcomes in the period before and after the introduction of TL for non-small cell lung cancer. Propensity score-matched analysis was performed with respect to baseline patient variables and tumor characteristics.
Results: Patients were divided into two groups: those who underwent lung lobectomy in the period before (BI group, n=261) and after (AI group, n=261) the introduction of TL. The proportion of TLs at our institution increased from 1.3% in the BI group to 93% in the AI group. The AI group experienced a longer duration of surgery, lesser intraoperative blood loss, and a significantly shorter postoperative hospital stay (POHS). There were no significant differences in postoperative complications between the two groups. The median follow-up period was 50 months in both groups. No significant differences were observed between the BI and AI groups with respect to 5-year overall survival (OS) (76.1% and 71.7%, respectively; P=0.1973) and disease-free survival (DFS) (67.6% and 66.1%, respectively; P=0.4071). On multivariate analysis, pathological N1–2 status was an independent predictor of survival. AI group and TL showed no independent association with survival.
Conclusions: The introduction of TL represented a positive change at our institution owing to decreased invasiveness and oncological equivalence of the surgical treatment for non-small cell lung cancer.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/23357}
}