TY - JOUR AU - Nashat, Heba AU - Montanaro, Claudia AU - Li, Wei AU - Kempny, Aleksander AU - Wort, Stephen J. AU - Dimopoulos, Konstantinos AU - Gatzoulis, Michael A. AU - Babu-Narayan, Sonya V. PY - 2018 TI - Atrial septal defects and pulmonary arterial hypertension JF - Journal of Thoracic Disease; Vol 10, Supplement 24 (September 2018): Journal of Thoracic Disease (Atrial Septal Defect) Y2 - 2018 KW - N2 - Atrial septal defects (ASD) are a common congenital heart defect. The majority of patient with ASDs often follow an uncomplicated course of events. However, a proportion of patients with ASDs, may have their condition complicated by pulmonary hypertension (PH), with a subsequent significant impact on management, morbidity and mortality. The presence of PH, influences the suitability for defect closure. In this review we describe the different types of ASDs, the classification of PH related to congenital heart disease (CHD), when ASD closure is contraindicated and the management of patients who develop pulmonary arterial hypertension (PAH), including the most extreme form, Eisenmenger syndrome (ES). UR - https://jtd.amegroups.org/article/view/23699