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The impact of histology and ground-glass opacity component on volume doubling time in primary lung cancer

  
@article{JTD23937,
	author = {Kai Obayashi and Kimihiro Shimizu and Seshiru Nakazawa and Toshiteru Nagashima and Toshiki Yajima and Takayuki Kosaka and Jun Atsumi and Natsuko Kawatani and Tomohiro Yazawa and Kyoichi Kaira and Akira Mogi and Hiroyuki Kuwano},
	title = {The impact of histology and ground-glass opacity component on volume doubling time in primary lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {9},
	year = {2018},
	keywords = {},
	abstract = {Background: Correlations between volume doubling time (VDT) of primary lung cancer (PLC), histology, and ground glass opacity (GGO) components remain unclear. The purpose of this study was to evaluate and compare VDT of PLC in terms of histology and presence or absence of GGO components.
Methods: A total of 371 surgically resected PLCs from 2003 to 2015 in our institute were retrospectively reviewed. The VDT was calculated both from the diameters of the entire tumor and of consolidation by using the approximation formula of Schwartz. 
Results: The median VDTs of adenocarcinoma, squamous cell carcinoma, and others (large cell neuroendocrine carcinomas, small cell lung carcinomas, pulmonary pleomorphic carcinomas, and large cell carcinomas combined) were 261, 70, and 70 days, respectively; these differ significantly (P},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/23937}
}