%0 Journal Article %T Intracellular signal transduction pathways as potential drug targets for ischemia-reperfusion injury in lung transplantation %A Huang, Lei %A Yang, Chengliang %A Liu, Mingyao %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Intracellular signal transduction pathways as potential drug targets for ischemia-reperfusion injury in lung transplantation %K %X Lung transplantation is the primary life-saving treatment option for patients with end stage lung disease. However, about 15−20% of donor lung recipients in the post-transplant period develop primary graft dysfunction, a severe form of ischemia/reperfusion (IR)-induced lung injury, which is a major cause of morbidity and mortality in the first year after transplantation. %U https://jtd.amegroups.org/article/view/24321 %P S3965-S3969 %@ 2077-6624