%0 Journal Article %T Significance of testing for TP53 gene mutations in lung adenocarcinoma using targeted gene sequencing %A Matsumura, Yuki %A Owada-Ozaki, Yuki %A Suzuki, Hiroyuki %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Significance of testing for TP53 gene mutations in lung adenocarcinoma using targeted gene sequencing %K %X Randomized clinical trials have demonstrated the positive effects of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for patients with advanced or recurrent lung adenocarcinomas harboring EGFR gene mutations (1-3). Detecting cancer-specific gene mutations and exploring their targeted therapies for advanced non-small cell lung cancer (NSCLC) have therefore become a major topic of discussion over the past decade. %U https://jtd.amegroups.org/article/view/24843 %P S4147-S4150 %@ 2077-6624