%0 Journal Article %T Successful rebuilding after disaster, even in the heart, starts with infrastructure %A Robich, Michael P. %A Ryzhov, Sergey %A Sawyer, Douglas B. %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Successful rebuilding after disaster, even in the heart, starts with infrastructure %K %X Mammalian heart regeneration has been the subject of intense debate and investigation among cardiovascular scientists for more than a century (1). While it is now widely accepted that the mammalian heart does have the capacity for self-renewal, replacement of injured tissue with new cardiomyocytes happens at a very low rate in the adult heart, and is not sufficient for the recovery of cardiac function after massive loss of cells (2). %U https://jtd.amegroups.org/article/view/25148 %P S4165-S4167 %@ 2077-6624